I would check the bulbs first.
If the bulbs are good, pull the fuses and check with a multimeter, they may look good, but if they have a micro fracture, they will look good but not work. Also make sure they seat correctly and the clips they plug into is not spread apart, bent or cracked.
if all the bulbs and fuses are good, you must have a loose connection or corroded connector somewhere. I would start at the fuse box and follow the wires, pulling each connector apart and examining it, maybe spray some wd-40 into it and reset it. Make sure none of the wires are poping out the back of the connector instead of plugging into where they are supposed to be.
I have also seen wires that have been crimped or are in a place like up by the handle bars where they are flexed back and forth by turning the handlebars and have broken, the outside insulator is still intact, but the wire inside broke and is no longer making contact. You can take each wire and pull it and see if it stretches apart, if so, you will need to cut it and splice it back together, I suggest soldering them since they will continue to flex at that point. I had this problem with a 1970s CX500 I had, around 8 wires had flexed so many times they snapped apart.
Great reply OhioTim. I just noticed that I have a very similar issue to Stu's on my 83' cb650sc. Thanks for the advice. I guess I know what I am doing tonight now :)